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Index > Protein center > SMAD1(Gene name) > Bovine
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  • SMAD1 (Gene name),
  • Mothers against decapentaplegic homolog 1 (Protein name ),  SMAD1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Gene name:
    SMAD1;
    Protein name:
    Mothers against decapentaplegic homolog 1(MAD homolog 1;Mothers against DPP homolog 1);
    Alternative:
    SMAD family member 1(SMAD 1;Smad1);
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Interacts with HGS, NANOG and ZCCHC12 (By similarity). May form trimers with another SMAD1 and the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit, CREB-binding protein (CBP), p300, SMURF1, SMURF2 and HOXC8. Associates with ZNF423 or ZNF521 in response to BMP2 leading to activate transcription of BMP target genes. Interacts with SKOR1. Interacts (via MH2 domain) with LEMD3. Binding to LEMD3 results in at least a partial reduction of receptor-mediated phosphorylation.
    Function:
    Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).
    Subcellular Location:
    Cytoplasm Nucleus Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane (By similarity). Forms a ternary complex with PSMB4 and OAZ1 before PSMB4 is incorporated into the 20S proteasome.
    Protein Attributes:
    Sequence length:
    465
    Sequence:
    50:
    MNVTSLFSFT | SPAVKRLLGW | KQGDEEEKWA | EKAVDALVKK | LKKKKGAMEE | 
    100:
    LEKALSCPGQ | PSNCVTIPRS | LDGRLQVSHR | KGLPHVIYCR | VWRWPDLQSH | 
    150:
    HELKPLECCE | FPFGSKQKEV | CINPYHYKRV | ESPVLPPVLV | PRHSEYNPQH | 
    200:
    SLLAQFRNLG | QNEPHMPLNA | TFPDSFQQPN | SHPFPHSPNS | SYPNSPGSSS | 
    250:
    STYPHSPTSS | DPGSPFQMPA | DTPPPAYLPP | EDPMTQDGSQ | PMDTNMMAPS | 
    300:
    LPSEINRGDV | QAVAYEEPKH | WCSIVYYELN | NRVGEAFHAS | STSVLVDGFT | 
    350:
    DPSNNKNRFC | LGLLSNVNRN | STIENTRRHI | GKGVHLYYVG | GEVYAECLSD | 
    400:
    SSIFVQSRNC | NYHHGFHPTT | VCKIPSGCSL | KIFNNQEFAQ | LLAQSVNHGF | 
    450:
    ETVYELTKMC | TIRMSFVKGW | GAEYHRQDVT | STPCWIEIHL | HGPLQWLDKV | 
    465:
    LTQMGSPHNP | ISSVS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine MAD homolog 1
    Cat.:
    E0647h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine MAD homolog 1
    Cat.:
    E0647b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine MAD homolog 1
    Cat.:
    E0647m
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    Packing:
    96T
    ELISA Kit for Bovine MAD homolog 1
    Cat.:
    E0647r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine MAD homolog 1
    Cat.:
    U0647m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine MAD homolog 1
    Cat.:
    U0647r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine MAD homolog 1
    Cat.:
    U0647h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MAD homolog 1
    Cat.:
    U0647b
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Bovine MAD homolog 1
    Cat.:
    P0647Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine MAD homolog 1
    Cat.:
    P0647Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine MAD homolog 1
    Polyclonal Antibody for Bovine MAD homolog 1
    Cat.:
    P0647Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine MAD homolog 1
    Monoclonal Antibody for Bovine MAD homolog 1
    Monoclonal Antibody for Bovine MAD homolog 1
    Monoclonal Antibody for Bovine MAD homolog 1
    Protein for Bovine MAD homolog 1
    Protein for Bovine MAD homolog 1
    Protein for Bovine MAD homolog 1
    Protein for Bovine MAD homolog 1

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    References
    1. 1.
      "Cloning and bioinformatic analysis of cDNA encoding cattle Smad1 gene."
      Zhang X. , Xu S.
      Submitted (2006-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Ascending colon.
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